• B.S., 1996, Chemical Engineering, Dalian University of Technology, China
  • M.S., 1999, Chemical Engineering (Biochemical Engineering), Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China
  • Ph.D., 2003, Plant Biology (Fungal Genetics and Biology), University of Georgia, USA
  • Postdoctoral research, 2007, Molecular Genetics and Microbiology (Medical Mycology), Duke University Medical Center, USA

Joined the Department of Biology in 2008

Joint Associate Professor, Department of Microbiology and Immunology, Texas A&M Health Science Center

BWF Investigator in Pathogenesis of Infectious Disease

Member of Faculty of 1000


  1. ICAAC Young Investigator Award, the American Society of Microbiology (ASM), 2009
  2. Teaching Excellence Award (SLATE), TAMU, 2009
  3. Eukaryotic Cell Outstanding Young Investigator Award, the American Society of Microbiology (ASM), 2009
  4. Teaching Excellence Award (SRATE), TAMU, 2011
  5. The Burroughs Wellcome Fund Investigator in Pathogenesis of Infectious Disease, 2013

Lin Lab Website


Research in our laboratory focuses on medical mycology:  We study the molecular mechanisms of fungal pathogenesis and microbial communication and development.  We investigate novel drugs that have the potential to be used to treat fungal infections and we are interested in characterizing fungal molecules that are promising vaccine candidates.  The long term goal of our research is to seek better approaches for treating fungal diseases and to advance our knowledge of eukaryotic microbiology. Please check Lin Lab webpage for more details.

  1. Gyawali, R, Upadhyay, S, Way, J, Lin, X. A Family of Secretory Proteins Is Associated with Different Morphotypes in Cryptococcus neoformans. Appl. Environ. Microbiol. 2017;83 (5):. doi: 10.1128/AEM.02967-16. PubMed PMID:28039134 PubMed Central PMC5311391.
  2. Upadhyay, S, Xu, X, Lin, X. Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation. MBio. 2016;7 (6):. doi: 10.1128/mBio.01925-16. PubMed PMID:27879337 PubMed Central PMC5120144.
  3. Upadhyay, S, Xu, X, Lowry, D, Jackson, JC, Roberson, RW, Lin, X et al.. Subcellular Compartmentalization and Trafficking of the Biosynthetic Machinery for Fungal Melanin. Cell Rep. 2016;14 (11):2511-8. doi: 10.1016/j.celrep.2016.02.059. PubMed PMID:26972005 PubMed Central PMC4805463.
  4. Xu, X, Zhao, Y, Kirkman, E, Lin, X. Secreted Acb1 Contributes to the Yeast-to-Hypha Transition in Cryptococcus neoformans. Appl. Environ. Microbiol. 2015;82 (4):1069-79. doi: 10.1128/AEM.03691-15. PubMed PMID:26637591 PubMed Central PMC4751841.
  5. Chacko, N, Zhao, Y, Yang, E, Wang, L, Cai, JJ, Lin, X et al.. The lncRNA RZE1 Controls Cryptococcal Morphological Transition. PLoS Genet. 2015;11 (11):e1005692. doi: 10.1371/journal.pgen.1005692. PubMed PMID:26588844 PubMed Central PMC4654512.
  6. Zhai, B, Wozniak, KL, Masso-Silva, J, Upadhyay, S, Hole, C, Rivera, A et al.. Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants. MBio. 2015;6 (5):e01433-15. doi: 10.1128/mBio.01433-15. PubMed PMID:26443458 PubMed Central PMC4611043.
  7. Wang, L, Lin, X. The morphotype heterogeneity in Cryptococcus neoformans. Curr. Opin. Microbiol. 2015;26 :60-4. doi: 10.1016/j.mib.2015.06.003. PubMed PMID:26094087 .
  8. Idnurm, A, Lin, X. Rising to the challenge of multiple Cryptococcus species and the diseases they cause. Fungal Genet. Biol. 2015;78 :1-6. doi: 10.1016/j.fgb.2015.05.002. PubMed PMID:25983191 PubMed Central PMC4461476.
  9. Lin, J, Idnurm, A, Lin, X. Morphology and its underlying genetic regulation impact the interaction between Cryptococcus neoformans and its hosts. Med. Mycol. 2015;53 (5):493-504. doi: 10.1093/mmy/myv012. PubMed PMID:25841056 PubMed Central PMC4577057.
  10. Lin, X, Chacko, N, Wang, L, Pavuluri, Y. Generation of stable mutants and targeted gene deletion strains in Cryptococcus neoformans through electroporation. Med. Mycol. 2015;53 (3):225-34. doi: 10.1093/mmy/myu083. PubMed PMID:25541555 PubMed Central PMC4574871.
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*Corresponding author

Xiaorong Lin

Xiaorong Lin
Associate Professor

3258 TAMU
College Station, TX 77843-3258

Biological Sciences Building West
Room 435D

Biological Sciences Building West
Room 435

Fax: 979-845-2891
Email: xlin@bio.tamu.edu

Curriculum Vitae